KMID : 0613820100200101483
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Journal of Life Science 2010 Volume.20 No. 10 p.1483 ~ p.1489
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The Effect of 4 Weeks of Treadmill Exercise and Protein Diet on Immunoglobulin and Antioxidant Enzyme in Rats
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Lee Chan-Soo
Lee Sang-Ho Sung Gi-Dong Baek Yeong-Ho
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Abstract
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The purpose of this study was to investigate the effects of treadmill exercise and a protein diet on immunoglobulin and antioxidant enzymes in rats. Forty-four male Sprague-Dawley rats, 5 weeks old, were used. Experimental groups were divided into exercise with protein diet group (A, n=11), exercise group (B, n=11), protein diet group (C, n=11), and the control group (D, n=11). Exercise was administered through a treadmill running program (14¢¦18 m/min, 0¡Æ grade, 20 min/day, 5 day/wk) and these rats were given a 40% protein diet for 4 wk. The results of this study are as follows: the protein diet group showed a significant increase in IgG of immunoglobulin compared to the exercise group and control group; the exercise with protein diet group and protein diet group showed a significant increase in SOD activity of antioxidant enzymes compared to the control group; the exercise with protein diet group, exercise group and protein diet group showed a significant increase in GPx activity of antioxidant enzymes compared to the control group; the exercise with protein diet group showed a significant increase in CAT activity of antioxidant enzymes compared to the protein diet group and control group. In conclusion, treadmill exercise and a protein diet were found to help with immunoglobulin and antioxidant enzymes. Further research regarding the effects of exercise and protein diets is required.
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KEYWORD
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Protein diet, antioxidant enzyme, immunoglobulin
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